You don't want to get rid of that 00 REG 22, because (1) you can't, (2) it's normal, and (3) it's useful.
00 REG nn -- that's what's always shown when you do any of the following in program mode:
• GTO . .
• Delete step 1 of any program
• Press backspace on the .END. when the current program is empty
The nn is the number of free registers in main memory, same as shown at the end of CAT 1. On a 41CX, MEMORY LOST / PRGM --> 00 REG 219, which means 219*7+4 = 1537 bytes available for programming. Coincidence: My PPC member number was 1537.